Title : Adult mice lacking the type 2 iodothyronine deiodinase have increased subchondral bone but normal articular cartilage.

Pub. Date : 2015 Mar

PMID : 25549200






2 Functional Relationships(s)
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1 Recent studies identified the DIO2 gene encoding type 2 deiodinase (D2) as a susceptibility locus for OA, and further data suggest deiodinase-regulated local availability of triiodothyronine (T3) in the joint plays an important role in cartilage maintenance and repair. Triiodothyronine deiodinase, iodothyronine, type II Mus musculus
2 Recent studies identified the DIO2 gene encoding type 2 deiodinase (D2) as a susceptibility locus for OA, and further data suggest deiodinase-regulated local availability of triiodothyronine (T3) in the joint plays an important role in cartilage maintenance and repair. Triiodothyronine deiodinase, iodothyronine, type II Mus musculus