Title : MicroRNA-130b regulates scleroderma fibrosis by targeting peroxisome proliferator-activated receptor γ.

Pub. Date : 2015 Jul

PMID : 25547017






1 Functional Relationships(s)
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1 Similar to human SSc, the same expression patterns of miR-130b, PPARgamma, and fibrosis-related genes were observed in the bleomycin-induced skin fibrosis model; TGF-beta induced the expression of miR-130b and fibrosis-related genes expression, but downregulated the expression of PPARgamma. Bleomycin transforming growth factor beta 1 Homo sapiens