Title : Etanercept alleviates early brain injury following experimental subarachnoid hemorrhage and the possible role of tumor necrosis factor-α and c-Jun N-terminal kinase pathway.

Pub. Date : 2015 Mar

PMID : 25542238






2 Functional Relationships(s)
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1 SP600125, Ach, and etanercept significantly decreased the level of pJNK and TNF-alpha in the cerebral cortex and the hippocampus. pyrazolanthrone tumor necrosis factor Homo sapiens
2 In addition, SP600125 and etanercept reduced cellular apoptosis in the cerebral cortex and the hippocampus and significantly improved neurological scores at 2 days after SAH potentially via inhibition of the JNK-TNF-alpha pathway. pyrazolanthrone tumor necrosis factor Homo sapiens