Pub. Date : 1989 Nov
PMID : 2554058
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recent evidence suggests that the adenine compounds ATP, adenosine-5"-O-(3-thiotriphosphate) (ATP gamma S), and adenosine have important regulatory effects on O2- responses of human neutrophils stimulated with the chemotactic peptide N-formyl-Met-Leu-Phe (fMLP). | adenosine 5'-O-(3-thiotriphosphate) | formyl peptide receptor 1 | Homo sapiens |
| 2 | Incubation of neutrophils with ATP gamma S or adenosine led to a decrease in numbers of fMLP receptors (17 and 9.2%, respectively) but no change in receptor affinity (Kd). | adenosine 5'-O-(3-thiotriphosphate) | formyl peptide receptor 1 | Homo sapiens |
| 3 | Paradoxically, ATP gamma S caused an increase in CR3 receptors (Mo1, CD-11b antigen), suggesting that fMLP and CR3 receptors may be under separate control. | adenosine 5'-O-(3-thiotriphosphate) | formyl peptide receptor 1 | Homo sapiens |