Pub. Date : 2015 Jul
PMID : 25536389
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of NAD on PARP-mediated insulin sensitivity in oleic acid treated hepatocytes. | Oleic Acid | insulin | Homo sapiens |
| 2 | Furthermore, treatment with PJ34 reversed the oleic acid-induced decrease in intracellular NAD concentration, while exogenous NAD protected cells against oleic acid-induced insulin insensitivity. | Oleic Acid | insulin | Homo sapiens |
| 3 | Taken together, these data suggest that NAD depletion by PARP1 activation is essential for the modulation of insulin sensitivity in oleic acid-induced lipotoxicity. | Oleic Acid | insulin | Homo sapiens |