Pub. Date : 2015 Aug
PMID : 25536367
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The objective of this study was to determine whether starting L-citrulline after the onset of pulmonary hypertension inhibits disease progression and improves NO production by recoupling endothelial NO synthase (eNOS). | Citrulline | nitric oxide synthase 3 | Homo sapiens |
| 2 | NO production and eNOS dimer-to-monomer ratios were greater in pulmonary arteries from L-citrulline-treated than from untreated hypoxic animals but were lower than in normoxic controls. | Citrulline | nitric oxide synthase 3 | Homo sapiens |
| 3 | When started after disease onset, oral L-citrulline treatment improves NO production by recoupling eNOS and inhibits the further development of chronic hypoxia-induced pulmonary hypertension in newborn piglets. | Citrulline | nitric oxide synthase 3 | Homo sapiens |