Title : B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: modulation by BCR and CD40, and relevance to T-independent antibody responses.

Pub. Date : 2015 Feb

PMID : 25536171






1 Functional Relationships(s)
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Protein Name
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1 Consistent with the requirement for dual TLR and BCR engagement in CSR induction, LPS, which engages TLR4 through its lipid A moiety, triggered cytosolic Ca2+ flux in B cells through its BCR-engaging polysaccharidic moiety. Lipid A toll like receptor 4 Homo sapiens