Pub. Date : 1989 Jan
PMID : 2553385
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Stimulatory effects on erythropoietin response are observed with the addition of compounds affecting the cAMP level such as forskolin, phosphodiesterase inhibitor and cholera toxin only in the presence of erythropoietin. | Cyclic AMP | erythropoietin | Mus musculus |
2 | Stimulatory effects on erythropoietin response are observed with the addition of compounds affecting the cAMP level such as forskolin, phosphodiesterase inhibitor and cholera toxin only in the presence of erythropoietin. | Cyclic AMP | erythropoietin | Mus musculus |
3 | cAMP analogues themselves show no stimulatory effect on TSA8 cells, nor does erythropoietin increase cAMP level in the cells. | Cyclic AMP | erythropoietin | Mus musculus |
4 | Thus, it is suggested that cAMP does not act as a direct second messenger for signal transduction through erythropoietin receptors, but as a stimulator of the erythropoietin receptor pathway and/or as a second messenger in combination with the receptor pathway. | Cyclic AMP | erythropoietin | Mus musculus |
5 | Thus, it is suggested that cAMP does not act as a direct second messenger for signal transduction through erythropoietin receptors, but as a stimulator of the erythropoietin receptor pathway and/or as a second messenger in combination with the receptor pathway. | Cyclic AMP | erythropoietin | Mus musculus |