Title : Synthesis and pharmacological evaluation of dual ligands for melatonin (MT1/MT2) and serotonin 5-HT2C receptor subtypes (II).

Pub. Date : 2015 Jan 27

PMID : 25528336






1 Functional Relationships(s)
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1 Concomitant insertion of a hydroxymethyl in the beta-acetamide position and aliphatic groups in C-3 position produced a positive effect on both melatonin (MT1, MT2) and serotonin (5-HT2C) binding affinities. Serotonin 5-hydroxytryptamine receptor 2C Homo sapiens