Title : Physiology-based pharmacokinetics of caspofungin for adults and paediatrics.

Pub. Date : 2015 Jun

PMID : 25522788






2 Functional Relationships(s)
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1 Patients of the CASLAMB trial received CAS in combination with cyclosporine A (CsA), which leads to an increased AUC0-24h of CAS hypothetically due to an inhibition of the hepatic transport protein OATP1B1 by CsA. Cyclosporine solute carrier organic anion transporter family member 1B1 Homo sapiens
2 Patients of the CASLAMB trial received CAS in combination with cyclosporine A (CsA), which leads to an increased AUC0-24h of CAS hypothetically due to an inhibition of the hepatic transport protein OATP1B1 by CsA. Cyclosporine solute carrier organic anion transporter family member 1B1 Homo sapiens