Pub. Date : 2015 Mar
PMID : 25522687
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cholesterol-mediated surfactant dysfunction is mitigated by surfactant protein A. | Cholesterol | surfactant protein A1 | Homo sapiens |
| 2 | It was hypothesized that elevated cholesterol levels within surfactant inhibit human surfactant biophysical function and that these effects can be reversed by surfactant protein A (SP-A). | Cholesterol | surfactant protein A1 | Homo sapiens |
| 3 | It was hypothesized that elevated cholesterol levels within surfactant inhibit human surfactant biophysical function and that these effects can be reversed by surfactant protein A (SP-A). | Cholesterol | surfactant protein A1 | Homo sapiens |
| 4 | It is concluded that cholesterol-induced surfactant inhibition can actively contribute to physiological impairment of the lungs in mechanically ventilated patients and that SP-A levels may be important to maintain surfactant function in the presence of high cholesterol within surfactant. | Cholesterol | surfactant protein A1 | Homo sapiens |