Pub. Date : 2014 Dec 15
PMID : 25517035
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UNLABELLED: The enzymatic reactivity of a series of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans; BFXs) towards mammalian single-electron transferring NADPH:cytochrome P-450 reductase (P-450R) and two-electron (hydride) transferring NAD(P)H: quinone oxidoreductase (NQO1) was examined in this work. | NADP | cytochrome p450 oxidoreductase | Homo sapiens |
| 2 | UNLABELLED: The enzymatic reactivity of a series of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans; BFXs) towards mammalian single-electron transferring NADPH:cytochrome P-450 reductase (P-450R) and two-electron (hydride) transferring NAD(P)H: quinone oxidoreductase (NQO1) was examined in this work. | NADP | cytochrome p450 oxidoreductase | Homo sapiens |
| 3 | The reduction of BFXs by both P-450R and NQO1 was accompanied by O2 uptake, which was much lower than the NADPH oxidation rate; except for annelated BFXs, whose reduction was followed by the production of peroxide. | NADP | cytochrome p450 oxidoreductase | Homo sapiens |