Pub. Date : 2014
PMID : 25514162
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Furthermore, DAT KO mice with reduced, but not eliminated, 5-HT1B receptor expression regained cocaine-stimulated locomotion, which was absent in DAT KO mice with normal levels of 5-HT1B receptor expression. | Cocaine | 5-hydroxytryptamine (serotonin) receptor 1B | Mus musculus |
2 | These findings of complementation of the locomotor effects of DAT KO by reducing 5-HT1B receptor activity underscore roles for interactions between specific 5-HT receptors and dopamine (DA) systems in basal and cocaine-stimulated locomotion and support evaluation of 5-HT1B antagonists as potential, non-stimulant ADHD therapeutics. | Cocaine | 5-hydroxytryptamine (serotonin) receptor 1B | Mus musculus |
3 | These findings of complementation of the locomotor effects of DAT KO by reducing 5-HT1B receptor activity underscore roles for interactions between specific 5-HT receptors and dopamine (DA) systems in basal and cocaine-stimulated locomotion and support evaluation of 5-HT1B antagonists as potential, non-stimulant ADHD therapeutics. | Cocaine | 5-hydroxytryptamine (serotonin) receptor 1B | Mus musculus |