Pub. Date : 2015 Apr
PMID : 25512114
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS: Thiadiazolidinone 8 (TDZD-8), a selective inhibitor of GSK-3beta, was administered intraperitoneally to 12-week-old MRL/lpr mice for 8 weeks or to 22-week-old (NZB x NZW)F1 mice for 12 weeks. | 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione | glycogen synthase kinase 3 beta | Mus musculus |
| 2 | METHODS: Thiadiazolidinone 8 (TDZD-8), a selective inhibitor of GSK-3beta, was administered intraperitoneally to 12-week-old MRL/lpr mice for 8 weeks or to 22-week-old (NZB x NZW)F1 mice for 12 weeks. | 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione | glycogen synthase kinase 3 beta | Mus musculus |
| 3 | TDZD-8 inhibited the activation of GSK-3beta and caspase 1, with a concomitant decrease in interleukin-1beta (IL-1beta) synthesis. | 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione | glycogen synthase kinase 3 beta | Mus musculus |