Title : Identification of metabolic pathways and enzyme systems involved in the in vitro human hepatic metabolism of dronedarone, a potent new oral antiarrhythmic drug.

Pub. Date : 2014 Jun

PMID : 25505590






1 Functional Relationships(s)
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1 N-debutyl-dronedarone was less rapidly metabolized than dronedarone, the major metabolic pathway being catalyzed by MAO-A to form propanoic acid-dronedarone and phenol-dronedarone. n-debutyl-dronedarone monoamine oxidase A Homo sapiens