Title : Alpinetin enhances cholesterol efflux and inhibits lipid accumulation in oxidized low-density lipoprotein-loaded human macrophages.

Pub. Date : 2015 Nov-Dec

PMID : 25496323






1 Functional Relationships(s)
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1 Small interfering RNA-mediated silencing of PPAR-gamma or LXR-alpha dose dependently reversed alpinetin-increased cholesterol efflux in THP-1 macrophages, indicating the involvement of PPAR-gamma and LXR-alpha in alpinetin-promoted cholesterol efflux. Cholesterol GLI family zinc finger 2 Homo sapiens