Title : Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3.

Pub. Date : 2015 Feb

PMID : 25496033






1 Functional Relationships(s)
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1 FXR knockdown abolished the inhibition of 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-Benzoic acid (GW4064) on JNK phosphorylation and ROS production induced by H2O2in HepG2 cells. GW 4064 nuclear receptor subfamily 1 group H member 4 Homo sapiens