Title : ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels.

Pub. Date : 2015

PMID : 25483068






1 Functional Relationships(s)
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1 Using genome-wide shRNA screening, we recently identified the ATM kinase as synthetic lethal with Nutlin-3, an MDM2 inhibitor that leads to non-genotoxic p53 activation. nutlin 3 tumor protein p53 Homo sapiens