Pub. Date : 2014
PMID : 25482947
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that inhibitors of the mTOR pathway including rapamycin, wortmannin, and caffeine blunted the p53 response to nucleolar stress induced by actinomycin D. | Dactinomycin | tumor protein p53 | Homo sapiens |
| 2 | Synthetic inhibitors of mTOR (temsirolimus, LY294.002 and PP242) also impaired actinomycin D triggered p53 stabilization and induction of p21. | Dactinomycin | tumor protein p53 | Homo sapiens |