Title : A systematic comparison of the impact of inflammatory signaling on absorption, distribution, metabolism, and excretion gene expression and activity in primary human hepatocytes and HepaRG cells.

Pub. Date : 2015 Feb

PMID : 25480923






1 Functional Relationships(s)
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1 Enzyme activities of CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, and CYP3A4 were reduced upon 48-72 hours exposure to IL-6 in PHH and HepaRG. 4,5,6,7-tetrachlorophthalide cytochrome P450 family 2 subfamily C member 19 Homo sapiens