Title : Possible direct linkage of insulin-like growth factor-II receptor with guanine nucleotide-binding proteins.

Pub. Date : 1989 Aug 25

PMID : 2547780






1 Functional Relationships(s)
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1 The IGF-II-mediated attenuation in the IAP substrate activity was 80% recovered after washing off IGF-II and inhibited by coexisting guanosine 5"-O-(2-thiodiphosphate), while either aluminum fluoride solution (10 mM NaF plus 100 microM AlCl3) or 100 microM guanosine 5"-O-(3-thiotriphosphate) (GTP gamma S) reproduced the action of IGF-II. guanosine 5"-o- insulin-like growth factor 2 Mus musculus