Title : Pyroptosis of resident macrophages differentially orchestrates inflammatory responses to Staphylococcus aureus in resistant and susceptible mice.

Pub. Date : 2015 Mar

PMID : 25472006






1 Functional Relationships(s)
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1 Treatment of DBA/2 susceptible mice with inflammasome inducers (i.e. nigericin and ATP) artificially increased pyroptosis and lowered the levels of NF-kappaB-related inflammatory cytokines, but restored IL-1beta to levels similar to those in C57BL/6 mice. Adenosine Triphosphate interleukin 1 beta Mus musculus