Title : Molecular classification of MYC-driven B-cell lymphomas by targeted gene expression profiling of fixed biopsy specimens.

Pub. Date : 2015 Jan

PMID : 25468432






1 Functional Relationships(s)
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1 Molecular analyses support the concept that there is a biological continuum between BL and DLBCL that includes variable activity of MYC, an oncoprotein once thought to be only associated with BL, but now recognized as a major predictor of survival among patients with DLBCL treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone). Cyclophosphamide MYC proto-oncogene, bHLH transcription factor Homo sapiens