Pub. Date : 1989 Jul 3
PMID : 2546796
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Potentiation by adrenaline of thrombin-induced elevation of pHi is not essential for synergistic activation of human platelets. | Epinephrine | coagulation factor II, thrombin | Homo sapiens |
2 | Adrenaline markedly enhanced the thrombin-induced increase in cytoplasmic pH (pHi) in BCECF-loaded platelets. | Epinephrine | coagulation factor II, thrombin | Homo sapiens |
3 | The potentiation by adrenaline of thrombin-induced PLC activation measured as [32P]PA formation and final platelet responses was, however, not blocked by EIPA, even at low concentrations of thrombin. | Epinephrine | coagulation factor II, thrombin | Homo sapiens |
4 | These results indicate that the enhancement by adrenaline of thrombin-induced cytoplasmic alkalinization may be a secondary effect which is not essential for the potentiation by adrenaline of platelet activation by thrombin. | Epinephrine | coagulation factor II, thrombin | Homo sapiens |