Title : Iodine inhibits the proliferation of rat thyroid cells in culture.

Pub. Date : 1989 Aug

PMID : 2546752






2 Functional Relationships(s)
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1 Iodide also inhibited the cAMP-dependent growth of FRTL5 cells induced by forskolin and (Bu)2cAMP, as well as the cAMP-independent mitogenesis induced by insulin-like growth factor-I. Iodides insulin-like growth factor 1 Rattus norvegicus
2 The effect of iodide to inhibit both TSH- and insulin-like growth factor-I-stimulated growth in FRTL5 cells was abolished by concomitant culture with methimazole, and no iodide inhibition of growth was observed in L6 myoblasts and BRL 30E hepatocytes. Iodides insulin-like growth factor 1 Rattus norvegicus