Title : Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts.

Pub. Date : 2015 Mar

PMID : 25466894






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The methyl donor S-adenosylmethionine (SAM) is produced in most cells through the folate cycle, but only a few cell types generate SAM from betaine (N,N,N-trimethylglycine) via betaine-homocysteine methyltransferase (BHMT), which is expressed in the mouse ICM. S-Adenosylmethionine betaine--homocysteine S-methyltransferase Homo sapiens
2 The methyl donor S-adenosylmethionine (SAM) is produced in most cells through the folate cycle, but only a few cell types generate SAM from betaine (N,N,N-trimethylglycine) via betaine-homocysteine methyltransferase (BHMT), which is expressed in the mouse ICM. S-Adenosylmethionine betaine--homocysteine S-methyltransferase Homo sapiens
3 The methyl donor S-adenosylmethionine (SAM) is produced in most cells through the folate cycle, but only a few cell types generate SAM from betaine (N,N,N-trimethylglycine) via betaine-homocysteine methyltransferase (BHMT), which is expressed in the mouse ICM. S-Adenosylmethionine betaine--homocysteine S-methyltransferase Homo sapiens