Title : Nest building is impaired in the Ts65Dn mouse model of Down syndrome and rescued by blocking 5HT2a receptors.

Pub. Date : 2014 Dec

PMID : 25463650






1 Functional Relationships(s)
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1 We show that both serotonin content and 5HT2a receptors are increased in the frontal cortex of Ts65Dn mice and that pharmacological blockage of 5HT2a receptors in Ts65Dn mice rescues their context dependent nest building impairment. Serotonin 5-hydroxytryptamine (serotonin) receptor 2A Mus musculus