Pub. Date : 2015 Jan 7
PMID : 25462276
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Deconstruction of 6,7-dimethoxytetrahydroisoquinoline moiety present in the potent mixed sigma2/P-gp agent 6,7-dimethoxy-2-[4-[1-(4-fluorophenyl)-1H-indol-3-yl]butyl]-1,2,3,4-tetrahydroisoquinoline (1) could lead to the separation of sigma2 affinity from P-gp activity. | 6,7-dimethoxy-2-[4-[1-(4-fluorophenyl)-1h-indol-3-yl]butyl]-1,2,3,4-tetrahydroisoquinoline | ATP binding cassette subfamily B member 1 | Homo sapiens |
2 | Deconstruction of 6,7-dimethoxytetrahydroisoquinoline moiety present in the potent mixed sigma2/P-gp agent 6,7-dimethoxy-2-[4-[1-(4-fluorophenyl)-1H-indol-3-yl]butyl]-1,2,3,4-tetrahydroisoquinoline (1) could lead to the separation of sigma2 affinity from P-gp activity. | 6,7-dimethoxy-2-[4-[1-(4-fluorophenyl)-1h-indol-3-yl]butyl]-1,2,3,4-tetrahydroisoquinoline | ATP binding cassette subfamily B member 1 | Homo sapiens |