Title : A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth.

Pub. Date : 2014 Nov 6

PMID : 25458841






3 Functional Relationships(s)
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Protein Name
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1 We show herein that the mitochondrial pyruvate carrier (MPC), composed of the products of the MPC1 and MPC2 genes, modulates fractional pyruvate oxidation. Pyruvic Acid mitochondrial pyruvate carrier 2 Homo sapiens
2 We show herein that the mitochondrial pyruvate carrier (MPC), composed of the products of the MPC1 and MPC2 genes, modulates fractional pyruvate oxidation. Pyruvic Acid mitochondrial pyruvate carrier 2 Homo sapiens
3 Cancer cells re-expressing MPC1 and MPC2 display increased mitochondrial pyruvate oxidation, with no changes in cell growth in adherent culture. Pyruvic Acid mitochondrial pyruvate carrier 2 Homo sapiens