Title : New efficient imidazolium aldoxime reactivators for nerve agent-inhibited acetylcholinesterase.

Pub. Date : 2014 Dec 15

PMID : 25453812






1 Functional Relationships(s)
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1 Compared with the known quaternary pyridinium reactivators, two of the resulting conjugates (7g and 7h) were highlighted to be the first efficient non-pyridinium oxime conjugates exhibiting similar or superior ability to reactivate sarin-, VX- and tabun-inhibited AChE. quaternary pyridinium acetylcholinesterase (Cartwright blood group) Homo sapiens