Title : Astroglial NMDA receptors inhibit expression of Kir4.1 channels in glutamate-overexposed astrocytes in vitro and in the brain of rats with acute liver failure.

Pub. Date : 2015 Sep

PMID : 25451797






1 Functional Relationships(s)
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1 Down-regulation of Kir4.1 transcription in rats with ALF was attenuated by intraperitoneal administration of a competitive NMDA receptor antagonist memantine, but not by histidine, which reverses ONS associated with ALF. Memantine potassium inwardly-rectifying channel, subfamily J, member 10 Rattus norvegicus