Pub. Date : 2014 Dec 5
PMID : 25451572
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The role of the efflux carriers Abcg2 and Abcc2 for the hepatobiliary elimination of benzo[a]pyrene and its metabolites in mice. | Benzo(a)pyrene | ATP binding cassette subfamily G member 2 (Junior blood group) | Mus musculus |
| 2 | As a consequence, [(3)H]BP concentrations were in general higher in the plasma and in most of the organs of the Abcg2 and Abcc2 knockout mice. | Benzo(a)pyrene | ATP binding cassette subfamily G member 2 (Junior blood group) | Mus musculus |
| 3 | Subjects with reduced ABCG2 or ABCC2 expression might have higher oral bioavailability for BP due to a reduced excretion and so might be more susceptible to BP-induced carcinogenesis. | Benzo(a)pyrene | ATP binding cassette subfamily G member 2 (Junior blood group) | Mus musculus |
| 4 | Subjects with reduced ABCG2 or ABCC2 expression might have higher oral bioavailability for BP due to a reduced excretion and so might be more susceptible to BP-induced carcinogenesis. | Benzo(a)pyrene | ATP binding cassette subfamily G member 2 (Junior blood group) | Mus musculus |