Pub. Date : 2014 Dec 15
PMID : 25446924
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Quercetin, luteolin and epigallocatechin gallate alleviate TXNIP and NLRP3-mediated inflammation and apoptosis with regulation of AMPK in endothelial cells. | epigallocatechin gallate | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Quercetin, luteolin and EGCG reduced reactive oxygen species production and inhibited TXNIP and NLRP3 inflammasome activation, lead to the downregulation of IL-1beta expression. | epigallocatechin gallate | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | In conclusion, quercetin, luteolin and EGCG inhibited ER stress-associated TXNIP and NLRP3 inflammasome activation, and thereby protected endothelial cells from inflammatory and apoptotic damage. | epigallocatechin gallate | NLR family pyrin domain containing 3 | Homo sapiens |