Title : The role of ventral midline thalamus in cholinergic-based recovery in the amnestic rat.

Pub. Date : 2015 Jan 29

PMID : 25446352






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1 Using the pyrithiamine-induced thiamine deficiency (PTD) rat model of human Wernicke-Korsakoff syndrome, we tested the hypothesis that co-infusion of the acetylcholinesterase inhibitor physostigmine across the PFC and HPC would recover spatial alternation performance in PTD rats. Physostigmine acetylcholinesterase (Cartwright blood group) Homo sapiens