Title : Antiarrhythmic efficacy of CPUY102122, a multiple ion channel blocker, on rabbits with ischemia/reperfusion injury.

Pub. Date : 2014 Dec

PMID : 25443730






2 Functional Relationships(s)
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Protein Name
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1 Cx43 expression in the left ventricle was significantly increased by CY22 treatment, which significantly decreased np-43 expression, Rac-1 activity and gp-91[phox] protein expression. cy22 gap junction alpha-1 protein Oryctolagus cuniculus
2 CONCLUSIONS: These results indicated that CY22 has both antiarrhythmic and cardiovascular protective effects partly by blocking IKr, the production of antioxidants and protection of Cx43. cy22 gap junction alpha-1 protein Oryctolagus cuniculus