Title : Miniature multi-channel SPR instrument for methotrexate monitoring in clinical samples.

Pub. Date : 2015 Feb 15

PMID : 25441416






1 Functional Relationships(s)
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1 MTX concentrations in a patient"s serum undergoing chemotherapy treatments can be determined by surface plasmon resonance (SPR) sensing using folic acid-functionalized gold nanoparticles (FA-AuNP) in competition with MTX for the bioreceptor, human dihydrofolate reductase (hDHFR) immobilized on the SPR sensor chip. Folic Acid dihydrofolate reductase Homo sapiens