Title : Interleukin 1 regulation of interleukin 2 and interferon-gamma gene activation in a human leukemic HSB.2 subclone.

Pub. Date : 1989

PMID : 2542734






1 Functional Relationships(s)
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1 Taken collectively, these experiments support the notion that IL1 does not trigger IL2 gene activation per se, but amplifies the preactivated lymphokine genes initiated by PMA and ionomycin, whereas IL1 can activate the IL2 receptor gene without any other known signal requirements. Tetradecanoylphorbol Acetate interleukin 1 alpha Homo sapiens