Title : Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.

Pub. Date : 2015

PMID : 25424545






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The quantitative relationship was evaluated between strain-, dose, and time-dependent formation of TCE metabolites from cytochrome P-450-mediated oxidation (trichloroacetic acid [TCA], dichloroacetic acid [DCA], and trichloroethanol) and glutathione conjugation [S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)glutathione], and various kidney toxicity phenotypes. 2,2,2-trichloroethanol cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus