Title : Signal transduction pathway for IL-1. Involvement of a pertussis toxin-sensitive GTP-binding protein in the activation of adenylate cyclase.

Pub. Date : 1989 Jun 15

PMID : 2542409






2 Functional Relationships(s)
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1 The inhibition by PT was associated with a decrease in IL-1-mediated cAMP production. Cyclic AMP interleukin 1 alpha Homo sapiens
2 PT also inhibited IL-1-stimulated cAMP production in crude membrane fractions from 7OZ/3, YT, and 3T3 fibroblasts. Cyclic AMP interleukin 1 alpha Homo sapiens