Title : Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy.

Pub. Date : 2014 Dec 16

PMID : 25422468






2 Functional Relationships(s)
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1 Treatment of diabetic ZDF rats with losartan, an angiotensin II receptor-1 (Agtr1) antagonist, attenuated the development of nephropathy and down-regulated renal cortical CB1R expression, without affecting the marked hyperglycemia. Losartan angiotensin II receptor, type 1a Rattus norvegicus
2 Treatment of diabetic ZDF rats with losartan, an angiotensin II receptor-1 (Agtr1) antagonist, attenuated the development of nephropathy and down-regulated renal cortical CB1R expression, without affecting the marked hyperglycemia. Losartan angiotensin II receptor, type 1a Rattus norvegicus