Pub. Date : 2017 Mar
PMID : 25414128
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that O-phenanthroline reduced the expression of MMP3 and MMP13 mRNA levels during chondrogenic differentiation of human chondrocytes (hChs), as well as after TNFalpha/IL-1beta exposure in an explant model. | 1,10-phenanthroline | tumor necrosis factor | Homo sapiens |
| 2 | Interestingly, O-phenanthroline significantly inhibited matrix degradation in a TNFalpha/IL-1beta-dependent model of cartilage degeneration when compared to control and natural hypoxia (2.5% O2 ). | 1,10-phenanthroline | tumor necrosis factor | Homo sapiens |