Title : Diminazene protects corpus cavernosum against hypercholesterolemia-induced injury.

Pub. Date : 2015 Feb

PMID : 25411084






2 Functional Relationships(s)
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1 MAIN OUTCOME MEASURES: ACE2 expression and its role in modulating nitric oxide (NO)/ROS production and fibrosis within the CC of hypercholesterolemic mice were the main outcome measures. Reactive Oxygen Species angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus
2 In accordance with that, pharmacological ACE2 activation by DIZE treatment reduced ROS production and NADPH oxidase expression, and elevated nNOS and eNOS expression and NO bioavailability in the penis of ApoE(-/-) mice. Reactive Oxygen Species angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus