Title : PPARĪ³ is involved in the hyperglycemia-induced inflammatory responses and collagen degradation in human chondrocytes and diabetic mouse cartilages.

Pub. Date : 2015 Mar

PMID : 25410618






2 Functional Relationships(s)
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1 Our data showed that high glucose induced the protein expressions of cyclooxygenase-2 (COX-2) and production of prostaglandin-E2 (PGE2 ), interleukin-6 (IL-6), and metalloproteinase-13 (MMP-13), but decreased the protein expression of collagen II and PPARgamma in human chondrocytes. Glucose interleukin 6 Homo sapiens
2 Our data showed that high glucose induced the protein expressions of cyclooxygenase-2 (COX-2) and production of prostaglandin-E2 (PGE2 ), interleukin-6 (IL-6), and metalloproteinase-13 (MMP-13), but decreased the protein expression of collagen II and PPARgamma in human chondrocytes. Glucose interleukin 6 Homo sapiens