Title : Pharmacological profile of opicapone, a third-generation nitrocatechol catechol-O-methyl transferase inhibitor, in the rat.

Pub. Date : 2015 Apr

PMID : 25409768






2 Functional Relationships(s)
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1 BACKGROUND AND PURPOSE: Catechol-O-methyltransferase (COMT) is an important target in the levodopa treatment of Parkinson"s disease; however, the inhibitors available have problems, and not all patients benefit from their efficacy. Levodopa catechol-O-methyltransferase Homo sapiens
2 BACKGROUND AND PURPOSE: Catechol-O-methyltransferase (COMT) is an important target in the levodopa treatment of Parkinson"s disease; however, the inhibitors available have problems, and not all patients benefit from their efficacy. Levodopa catechol-O-methyltransferase Homo sapiens