Pub. Date : 2014 Nov 13
PMID : 25408841
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Deletion of the SO2CH3 group of rofecoxib switches the compound from a COX-2- to a COX-1-selective inhibitor, providing a 3,4-diarylfuran-2(5H)-one scaffold for structure-activity relationship studies of COX-1 inhibition. | rofecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |