Title : Effects of rifampin, cyclosporine A, and probenecid on the pharmacokinetic profile of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in healthy participants.

Pub. Date : 2015 Feb

PMID : 25407255






1 Functional Relationships(s)
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1 Canagliflozin exposures may be affected by coadministration of drugs that induce (e.g., rifampin for UGT) or inhibit (e.g. probenecid for UGT; cyclosporine A for P-gp) these pathways. Cyclosporine ATP binding cassette subfamily B member 1 Homo sapiens