Title : Genetic disruption of lactate/H+ symporters (MCTs) and their subunit CD147/BASIGIN sensitizes glycolytic tumor cells to phenformin.

Pub. Date : 2015 Jan 1

PMID : 25403912






1 Functional Relationships(s)
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1 Consequently, cells accumulated an intracellular pool of lactic and pyruvic acids, magnified by the MCT1 inhibitor decreasing further pHi and glycolysis. Pyruvic Acid solute carrier family 16 member 1 Homo sapiens