Title : Lenalidomide interferes with tumor-promoting properties of nurse-like cells in chronic lymphocytic leukemia.

Pub. Date : 2015 Feb

PMID : 25398834






1 Functional Relationships(s)
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1 We found that lenalidomide induces high actin polymerization on CD14(+) monocytes through activation of small GTPases, RhoA, Rac1 and Rap1 that correlated with increased adhesion and impaired monocyte migration in response to CCL2, CCL3 and CXCL12. Lenalidomide CD14 molecule Homo sapiens