Title : Oxidative stress by monosodium urate crystals promotes renal cell apoptosis through mitochondrial caspase-dependent pathway in human embryonic kidney 293 cells: mechanism for urate-induced nephropathy.

Pub. Date : 2015 Jan

PMID : 25398539






1 Functional Relationships(s)
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1 MSU crystals promoted ROS, iNOS, and COX-2 expression and also increased TRAF-6 and IL-1beta expression in HEK293 cells, which was inhibited by an antioxidant ascorbic acid. Ascorbic Acid LOC222344 Homo sapiens