Title : Hyperinsulinemia induces hepatic iron overload by increasing liver TFR1 via the PI3K/IRP2 pathway.

Pub. Date : 2014 Dec

PMID : 25385842






1 Functional Relationships(s)
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1 Insulin-induced TFR1 expression was blocked by IRP2, but not by IRP1 interference, and disappeared when HL-7702 cells were pretreated with LY294002, triciribine hydrate, or rapamycin. triciribine transferrin receptor Rattus norvegicus